Biomaterials-based Strategies for Endogenous Tissue Regeneration - 2

Timeslot: Wednesday, April 21, 2021 - 4:45pm to 6:15pm
Room: Virtual


Large tissue defects are still challenging to be effectively repaired by using current methods. Instead of relying on a large number of exogenous cells and/or proteins-based tissue engineering approaches, the strategies that using biomaterials to promote tissue regeneration by activating and harnessing endogenous reparative cells and signaling pathways are more promising and translational. Interesting endogenous signaling pathways that contribute to tissue regeneration include but not limited to angiogenesis, inflammation, stem cell recruitment, and differentiation, etc. This session will focus on introducing the emerging concepts and strategies in the development of innovative biomaterials/drug/gene delivery/stem cell techniques for challenged tissue regeneration, e.g., cartilage, bone, teeth, skin, muscle, etc. Long term goal for this session is to develop new biomaterials-based regenerative treatments by using the body's innate ability through promoting the collaborations from the multidisciplinary filed.

Hongli Sun, PhD


Abstracts will be available for download on April 20, 2021.

  • 115. Controlling Osteogenesis by Grafting Peptide Mimetics via Orthogonal Click Chemistries to Alginate Hydrogels, Sydney Neal1, Era Jain, PhD1, Xiaohong Tan1, Hannah Graf2, Rama Balasubramaniam1, Nathaniel Huebsch, PhD11Washington University in St. Louis, St. Louis, MO, USA, 2Eberhard-Karls University, Tübingen, Germany

  • 116. Neurotization of Decellularized Muscle Matrix Improves Functional Recovery and Promotes Unique mRNA Profiles in a Volumetric Muscle Loss Model, James Redden, B.S. Biomedical Engineering, David Cohen, Lucas Olson, Luke Krebs, Gettanjali Bendale, Jonathan Isaacs, Zvi Schwartz, Michael McClureVirginia Commonwealth University, Richmond, VA, USA

  • 117. The Macroarchitecture of Biomimetic Proteoglycans is Responsible for the Micromolecular Engineering of Cartilage Pericellular Matrix, Elizabeth Kahle1, Biao Han, PhD1, Prashant Chandrasekaran, PhD1, Katsiaryna Prudnikova, PhD1, Michele Marcolongo, PhD, PE1,2, Lin Han, PhD11Drexel University, Philadelphia, PA, USA, 2Villanova University, Villanova, PA, USA

  • 118. Enhanced satellite cell differentiation and muscle regeneration by semi-synthetic Hyaluronic acid hydrogel-mediated delivery of Fibro-Adipogenic Progenitors in Volumetric Muscle Loss, Shane Browne, PhD1, Anouk Killaars, PhD1, Mengyao Liu, BA2, Xuhui Li, MD2, Hubert Kim, MD, PhD2, Brian Feeley, MD2, Kevin Healy, PhD11University of California, Berkeley, Berkeley, CA, USA, 2University of California, San Francisco, San Francisco, CA, USA