Biomaterials Systems and Devices for Hemostasis, Resuscitation and Wound Care
Timeslot: Friday, April 23, 2021 - 11:00am to 12:30pm
Track: Cardiovascular Biomaterials
Hemorrhage control, hemodynamic resuscitation and spatio-temporal wound care via passive and/or bioactive mechanisms are important application areas of biomaterials-based technologies and includes external, intracavitary, and intravascular hemostats, nanoparticle/microparticle systems, artificial blood surrogates, dressings, powders, foams, fibers and gels. The goal of this session is to highlight recent advances in such biomaterials technologies that focus on hemostasis/thrombosis, hemodynamic stabilization, tissue oxygenation and wound healing. The proposed session will invite presentations from researchers in this field that discuss design of the biomaterials systems, structure-property-function relationships, and translational visions of such technologies. Presentations focused on material considerations for microdevices for investigating hemostatic and thrombotic pathways are also of interest for this session.
Ashley Brown, PhD
Shaunak Pandya, PhD
Abstracts will be available for download on April 20, 2021.
205. Engineering a highly elastic bioadhesive hydrogel for sealing soft and dynamic tissues, Mahsa Ghovvati, Sevana Baghdasarian, Avijit Baidya, Jharana Dhal, Nasim AnnabiUniversity of California, Los Angeles, Los Angeles, CA, USA
206. Role of Nitric Oxide-Releasing Glycosaminoglycans on In Vitro Wound Healing, Sara Maloney, Mark Schoenfisch, PhDUniversity of North Carolina at Chapel Hill, Chapel Hill, NC, USA
207. Controlled Oxygen Release to Accelerate Diabetic Wound Healing by Simultaneously Promoting Epithelialization and Angiogenesis, and Decreasing Tissue Inflammation, Ya Guan, Hong Niu, PhD, Jianjun Guan, PhDWashington University in St. Louis, St. Louis, MO, USA
208. Rupture of Fibrin Clots: Structural and Thermodynamic Mechanisms, Valerie Tutwiler1,2, Farkhad Maksudov3, Rustem Litvinov1,4, John Weisel1, Valeri Barsegov31University of Pennsylvania, Philadelphia PA, PA, USA, 2Rutgers - The State University of New Jersey, Piscataway, NJ, USA, 3University of Massachusetts, Lowell, Lowell, MA, USA, 4Kazan Federal University, Kazan, Russian Federation
209. Thrombin-triggered Shape Changing Nanogels for Development of Synthetic Platelets, Eunice Chee1,2, Emily Mihalko1,2, Ashley Brown, PhD1,21North Carolina State University and University of North Carolina - Chapel Hill, Raleigh, NC, USA, 2Comparative Medicine Institute, Raleigh, NC, USA
210. Injury-targeted Enzyme-responsive Direct Delivery of Thrombin for Hemostatic Treatment of Coagulopathy, Aditya Girish, Ketan Jolly, Ujjal Didar Singh Sekhon, Anirban Sen GuptaCase Western Reserve University, Cleveland, OH, USA