Biomaterials for Women's and Fetal Health *BTI*

Timeslot: Wednesday, April 21, 2021 - 4:45pm to 6:15pm
Room: Virtual


Maternal and fetal health are closely linked to long term health. Conditions such as preeclampsia can increase both a mother and child's risk for health complications including heart disease and high blood pressure later in life. Exposure to various environmental toxicants have been linked to increased risk of pregnancy complications such as gestational diabetes and miscarriage. Biomaterials can play an important role in understanding and promoting maternal and fetal health. These materials can be used to achieve new models, treatments, and diagnostics for prenatal and maternal healthcare. This session will cover advances in this field, including, but not limited to, organ-on-a-chip approaches to drug toxicity screening, development of models of the maternal-fetal interface, treatments for pregnancy complication (e.g., preterm birth, preeclampsia, etc.), placental membranes, biomechanics during pregnancy, new fertility treatments, and fetal cell isolation

Christaina Bailey-Hytholt, PhD
David Martin, PhD


Abstracts will be available for download on April 20, 2021.

  • 109. A Gelatin Hydrogel Model of the Endometrium and Trophoblast Invasion, Samantha Zambuto, ScM1, Ishita Jain1, Shemona Rattila2, Kathryn Clancy, PhD1, Gabriela Dveksler, PhD2, Gregory Underhill, PhD1, Brendan Harley, PhD11University of Illinois Urbana-Champaign, Urbana, IL, USA, 2Uniformed Services University of the Health Sciences, Bethesda, MD, USA

  • 110. Engineering Lipid Nanoparticles for In Utero mRNA Delivery, Margaret Billingsley, Michael Mitchell, PhDUniversity of Pennsylvania, Philadelphia, PA, USA

  • 111. Fully Absorbable Poly-4-hydroxybutyrate (P4HB) Scaffold Provides Mechanical Support at 12 months Following Vaginal Implantation in an Ovine Model, Zeliha Guler, PhD, University of Amsterdam, Amsterdam, Netherlands

  • 112. Design and Prototyping of Dynamic Midurethral Sling for The Treatment of Stress Urinary Incontinence, Seelay Tasmim1, Philippe Zimmern2, Taylor Ware11Texas A&M University, College Station, TX, USA, 2The University of Texas Southwestern Medical Center, Dallas, TX, USA

  • 113. Evaluation of Immunomodulatory Mesh for Pelvic Floor Reconstruction in a Rabbit Colpopexy Model, Bryan Brown, PhD1,2, Aimon Iftikhar, PhD1,2, Alexis Nolfi1,2, Clint Skillen1,2, Branimir Popovic, DVM1,2, Pamela Moalli, MD, PhD1,21University of Pittsburgh, Pittsburgh, PA, USA, 2McGowan Institute for Regenerative Medicine, Pittsburgh, PA, USA

  • 114. Poly-4-hydroxybutyrate (P4HB) Fully Absorbable Scaffolds for Soft Tissue Support in 3D Applications, David Martin, PhD, Kai Guo, PhD, Jeffrey Scott, PhD, Antonio Fosco, Amit Ganatra, Said RizkTepha, Inc., Lexington, MA, USA