Drug Delivery SIG 1
Timeslot: Thursday, April 22, 2021 - 11:00am to 12:30pm
Track: Therapeutic Delivery
The Drug Delivery Special Interest Group will deal with the science and technology of controlled release of active agents from delivery systems. Controlled drug release is achieved by the use of diffusion, chemical reactions, dissolutions or osmosis, used either singly or in combination. While the vast majority of such delivery devices are based on polymers, controlled release can also be achieved by the use of mechanical pumps. In a broader sense, controlled release also involves control over the site of action of the active agent, using the active agent using pro-drugs, targetable water soluble polymers or various microparticulate systems. Relevant aspects of toxicology, bioavailability, pharmacokinetics, and biocompatibility are also included.
Michael Mitchell, PhD
Omid Veiseh, PhD
Abstracts will be available for download on April 20, 2021.
139. Macrophage depletion increases target specificity of bone-targeted nanoparticles, Marian Ackun-Farmmer, Baixue Xiao, Danielle BenoitUniversity of Rochester, Rochester, NY, USA
140. Scalable Parallelized Microfluidic Device for Precise RNA Lipid Nanoparticle Formulations, Sarah Shepherd, BS, David Issadore, PhD, Michael Mitchell, PhDUniversity of Pennsylvania, Philadelphia, PA, USA
141. Uricase Functionalized Hydrogel for the Localized Treatment of Gout, Madeline Fuchs, Gregory Hudalla, PhD, Benjamin Keselowsky, PhDUniversity of Florida, Gainesville, FL, USA
142. A Potent Branched Tail Lipid Nanoparticle Enables Multiplexed mRNA Delivery and Gene Editing in vivo, Jilian Melamed, Khalid Hajj, Kathryn WhiteheadCarnegie Mellon University, Pittsburgh, PA, USA
143. In Vitro Evaluation of a Drug-Loaded Self-Assembling Peptide Hydrogel for Treating Glioblastoma Multiforme, Alexandra Nukovic, Megan Pitz, Margaret Elpers, Sarah Wilde, Arica Gregory, Angela Alexander-Bryant, PhDClemson University, Clemson, SC, USA
144. Scalable Production of pDNA/lPEI Nanoparticles via Kinetically Controlled Assembly for Gene Delivery with Enhanced Efficiency and Biocompatibility, Yizong Hu1, Il Minn, PhD1, Martin Pomper, MD, PhD1, Hai-Quan Mao, PhD21Johns Hopkins University School of Medicine, Baltimore, MD, USA, 2Johns Hopkins University, Baltimore, MD, USA|