Engineering Cells and Their Microenvironments SIG - 2

Timeslot: Thursday, April 22, 2021 - 11:00am to 12:30pm
Track: Engineered Microenvironments
Room: Virtual


This session will focus on research that describes biomaterials-based approaches for influencing cellular behaviors and fates, which include, for example, proliferation, differentiation, morphological state, motility, matrix production, and life/death. Advances in biomaterial technologies for engineering cells and their microenvironments play instrumental roles in discoveries ranging from elucidation of fundamental biological processes to translation of cellular and material systems to clinics and industry. Work in this area includes biomaterials and biomaterial systems that focus on controlling cells and their environments at the cell scale and talks will encompass engineering microenvironments, biomaterial-influenced cell signaling, technology used in stem cell manufacturing and differentiation, immunoengineering, and biomaterials for cell-based detection and diagnosis. Studies that will be highlighted will range from the development of biomimetic materials providing specific physicochemical cues that elicit desired phenotypic responses to work focused on applications of material systems at the cellular level, for example in cell-based and cell-focused therapies or in understanding the progression of disease, such as COVID-19.

Daniel Harrington, PhD
Chris Highley, PhD
Ram Saraswat, BS
Scott Wood, PhD


Abstracts will be available for download on April 20, 2021.

  • 151. Synthetic Hydrogels to Study ECM Dynamics of Intestinal Organoids, Michael Blatchley1, Arda Gunay1, Max Yavitt1, Peter Dempsey2, Kristi Anseth11University of Colorado Boulder, Boulder, CO, USA, 2University of Colorado School of Medicine, Aurora, CO, USA

  • 152. Dissecting the Microenvironmental Control of Liver Stellate Cell Epigenetics and Fibrogenic Phenotypes, Ishita Jain, Aidan Brougham-Cook, Gregory Underhill, PhDUniversity of Illinois at Urbana Champaign, Urbana, IL, USA

  • 153. Biasing Hematopoietic Response In Single-Cell Microenvironments, Aidan Gilchrist1, Julio Serrano1, Michael Hunckler2, Andres Garcia2, Brendan Harley11University of Illinois at Urbana-Champaign, Champaign, IL, USA, 2Georgia Institute of Technology, Atlanta, GA, USA

  • 154. Protease-Activatable Conjugates for Cell-Specific Targetting, Eugene Pashuck, PhD1, Samuel Rozans, Kayleigh Atanasoff, Abdul-Nafea Syed, Jake Tosh, Amanda Ferrante1Lehigh University, Bethlehem, PA, USA

  • 155. Development of an In-vitro Microphysiological Model of the Tracheal Epithelium, Solaleh Miar1, Yamuna Pillai1, Zina Helal1, Gregory R Dion2, Joo L Ong1, Rena Bizios1, Teja Guda11The University of Texas at San Antonio, San Antonio, TX, USA, 2US Army Institute of Surgical Research, San Antonio, TX, USA

  • 156. SARS-CoV-2 Spike Protein-Induced Toxicity in 3D Engineered Vascular Networks, Brett Stern, B.S., Janet Zoldan, PhDUniversity of Texas at Austin, Austin, TX, USA