Targeted and Stimuli-Responsive Biomaterials for Drug Delivery - 1
Timeslot: Wednesday, April 21, 2021 - 12:30pm to 2:00pm
Targeted and stimuli-responsive biomaterials, are promising for various applications in drug delivery. These "smart" materials can act rapidly at the site of interest while avoiding biological barriers, toxicity, and other potential detrimental effects. Many stimuli have been utilized to trigger stimuli-responsive materials including pH, temperature, ionic strength, chemical and/or mechanical microenvironment, redox potential, and light. Similarly, many targeting mechanisms ranging from passive (e.g., enhanced permeation and retention) to active targeting approaches (e.g., peptide ligands) have been integrated into targeted drug delivery systems. This session will focus on the development and use of such materials for applications including, but not limited to, cancer, infection, orthopedic diseases, cardiovascular disease, and autoimmune diseases.
Danielle Benoit, PhD
Abstracts will be available for download on April 20, 2021.
223. Injectable Acylhydrazone Hydrogels for Sustained Protein Release, Fang-Yi Lin, PhD, Nathan Dimmitt, Chien-Chi Lin, PhDIndiana University-Purdue University Indianapolis, Indianapolis, IN, USA
224. Polydopamine-Mesoporous Silica Core-Shell Nanoparticles for Combined Photothermal-Immunotherapy, Anushree Seth, PhD, Hamed Derami, Prashant Gupta, Zheyu Wang, Priya Gupta, Rohit Gupta, Thao Cao, Jeremiah Morrissey, PhD, Srikanth Singamaneni, PhD
225. Hydrolytically degradable hydrogels for therapeutic delivery, Maria Coronel, PhD, Karen Martin, Rahul Shah, Andres Garcia, PhDGeorgia Institute of Technology, Atlanta, GA, USA
226. Modular Oxygen-Generating Biomaterials for in situ Support of Cell-based Therapies, Robert Accolla1, Jia-Pu Liang1, Cherie Stabler, PhD1,21University of Florida, Gainesville, FL, USA, 2UF Diabetes Institute, Gainsville, FL, USA
227. Ultrasound-Controlled Release of Basic Fibroblast Growth Factor (bFGF) from Acoustically-Responsive Scaffolds Improves Recovery in the Murine Model of Hind Limb Ischemia, Hai Jin1,2, Carole Quesada1, Mitra Aliabouzar1, Oliver Kripfgans1, J. Brian Fowlkes1, Renny Franceschi1, Jianhua Liu2, Andrew Putnam1, Mario Fabiilli11University of Michigan, Ann Arbor, MI, USA, 2South China University of Technology, Guangzhou, China
228. Spatially-Directed Angiogenesis via the Ultrasound-Controlled Release of Basic Fibroblast Growth Factor (bFGF) from Acoustically-Responsive Scaffolds, Leidan Huang1,2, Carole Quesada1, Mitra Aliabouzar1, Oliver Kripfgans1, Renny Franceschi1, Zheng Liu2, Andrew Putnam1, Mario Fabiilli11University of Michigan, Ann Arbor, MI, USA, 2Second Affiliated Hospital of Army Medical University, Chongqing, China